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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANX
All Species:
25.15
Human Site:
S564
Identified Species:
36.89
UniProt:
P27824
Number Species:
15
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27824
NP_001019820.1
592
67568
S564
E
E
D
G
G
T
V
S
Q
E
E
E
D
R
K
Chimpanzee
Pan troglodytes
XP_001151304
592
67554
S564
E
E
D
G
G
T
V
S
Q
E
E
E
D
R
K
Rhesus Macaque
Macaca mulatta
XP_001101429
592
67582
S564
E
E
D
G
G
T
V
S
Q
E
E
E
D
R
K
Dog
Lupus familis
XP_533285
610
69806
I564
E
E
K
S
E
E
E
I
E
I
I
E
G
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P35564
591
67259
S563
E
E
D
G
V
T
G
S
Q
D
E
E
D
S
K
Rat
Rattus norvegicus
P35565
591
67236
S563
E
E
D
G
G
T
G
S
Q
D
E
E
D
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506871
598
67609
S567
E
E
E
V
G
N
A
S
Q
E
E
E
E
E
G
Chicken
Gallus gallus
NP_001025791
599
68090
E566
D
I
G
S
A
S
Q
E
E
E
E
E
E
E
E
Frog
Xenopus laevis
NP_001080326
611
69964
S577
D
E
E
E
G
K
E
S
Q
D
E
E
E
A
E
Zebra Danio
Brachydanio rerio
NP_998613
600
67856
S554
E
E
P
E
A
K
K
S
E
E
E
D
S
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
D384
D
K
D
D
E
D
E
D
D
D
D
E
E
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34652
619
69189
E580
S
Q
S
S
A
A
E
E
E
D
D
E
H
V
V
Sea Urchin
Strong. purpuratus
XP_791226
591
66512
E539
E
E
E
D
V
S
A
E
G
D
A
V
V
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
D398
E
E
D
D
E
K
A
D
E
D
K
A
D
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29402
530
60468
A503
E
K
K
K
P
E
V
A
E
S
S
K
S
G
D
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
I475
F
D
R
I
I
D
R
I
L
E
Q
P
L
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
59.1
N.A.
93
93.5
N.A.
85.7
82.8
78.2
70.8
N.A.
31.7
N.A.
40.5
53.7
Protein Similarity:
100
99.8
99.4
75.2
N.A.
96.6
97.4
N.A.
93.1
90.8
86.2
84.1
N.A.
44.7
N.A.
58.9
69.7
P-Site Identity:
100
100
100
20
N.A.
73.3
80
N.A.
53.3
20
40
33.3
N.A.
13.3
N.A.
6.6
20
P-Site Similarity:
100
100
100
40
N.A.
80
86.6
N.A.
66.6
53.3
73.3
46.6
N.A.
53.3
N.A.
33.3
46.6
Percent
Protein Identity:
N.A.
29.3
N.A.
40
25.6
N.A.
Protein Similarity:
N.A.
44.4
N.A.
53.5
41.2
N.A.
P-Site Identity:
N.A.
26.6
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
7
19
7
0
0
7
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
7
44
19
0
13
0
13
7
44
13
7
38
0
19
% D
% Glu:
69
69
19
13
19
13
25
19
38
44
57
69
25
13
19
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
7
32
38
0
13
0
7
0
0
0
7
7
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
7
7
0
0
13
0
7
7
0
0
0
0
% I
% Lys:
0
13
13
7
0
19
7
0
0
0
7
7
0
13
32
% K
% Leu:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
7
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
7
0
0
0
0
7
0
44
0
7
0
0
7
7
% Q
% Arg:
0
0
7
0
0
0
7
0
0
0
0
0
0
25
0
% R
% Ser:
7
0
7
19
0
13
0
50
0
7
7
0
13
19
0
% S
% Thr:
0
0
0
0
0
32
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
0
7
13
0
25
0
0
0
0
7
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _